Los Angeles | Oscar-winner Jessie Buckley is set to reunite with her "Hamnet" co-star Paul Mescal for director Benh Zeitlin's "Hold on to Your Angels".

Buckley won the best actress Oscar for her role in the Chloe Zhao's critically-acclaimed historical drama. Based on Maggie O'Farrell's novel, the story is a dramatised retelling of William Shakespeare and his wife Agnes Hathaway as they struggle with the death of their 11-year-old son, Hamnet.

The two actors also starred in Maggie Gyllenhaal's "The Lost Daughter", but had no scenes together.

"Hold on to Your Angels" is will be produced by Plan B and Rapt Film, according to the entertainment news outlet Deadline.

The story revolves around a hell-bound outlaw (Mescal) and a ferocious shepherd of lost souls (Buckley), who fall in a catastrophic love, as per the official logline.

"'Hold on to Your Angels' is the most impossible love story I've ever witnessed - an outlaw romance for the end of America, set on the crumbling edge of South Louisiana," the filmmaker, known for movies such as "Beasts of the Southern Wild", "Wendy" and "Glory at Sea", said in a statement.

"I've been dreaming of telling it since its hero, Pam Harper, walked into an audition for 'Beasts of the Southern Wild', 17 years ago. It's a love letter to an endangered way of life - and a rallying cry for empathy across a fractured planet," he added.

Rapt Film's Alex Coco said, "After years of working with filmmakers that explore the overlooked corners of our world, I can recognise Benh Zeitlin as a filmmaker with that rare gift: the ability to reveal profound beauty and humanity in parts of America that seldom find their way onto the silver screen."